MEDIX, God. 28 Br. 153/154  •  Pregledni članak  •  Oftalmologija HR ENG

Oftalmološke manifestacije mukokutanih buloznih bolestiOphthalmological manifestations of mucocutaneous bullous diseases

Lorena Karla Rudež, Igor Petriček, Maja Bakula, Iva Bešlić

Mukokutane bulozne bolesti obuhvaćaju široku skupinu bolesti obilježenu pojavom mjehura na koži i sluznicama. Najčešći oftalmološki simptomi u bolesnika s mukokutanim buloznim bolestima jesu svrbež i žuljanje očiju, osjećaj stranoga tijela, crvenilo i pojačano suzenje. Najčešće komplikacije su ožiljkavajući konjunktivitis, skraćenje forniksa, simblefaron, trihijaza, suho oko, defekt epitela rožnice, ulceracija i vaskularizacija te keratinizacija površine oka. Navedene promjene mogu dovesti do pada vidne oštrine te sljepoće. Liječenje oftalmoloških simptoma uglavnom se temelji na sustavnoj terapiji bolesti te lokalnom zbrinjavanju. Za povoljan ishod bolesti nužno je pravodobno postavljanje ispravne dijagnoze te interdisciplinarni pristup u obradi i liječenju bolesnika s buloznim dermatozama

Ključne riječi:
bulozna epidermoliza; epidermolysis bullosa aquisita; linearna IgA dermatoza; mukozni membranozni pemfigoid; pemphigus vulgaris

Članak u cijelosti pročitajte u tiskanom izdanju MEDIX, God. 28 Br. 153/154
narudžba izdanja

Mucocutaneous bullous diseases include a wide group of diseases characterized by the appearance of blisters on the skin and mucous membranes. The most common ocular symptoms in patients with mucocutaneous bullous diseases are itching and blistering of the eyes, foreign body sensation, redness, and increased lacrimation. The most common complications are cicatrizing conjunctivitis, shortening of the fornix, symblepharon, trichiasis, dry eye, corneal epithelial defect, ulceration and vascularization, and ocular surface keratinization. The mentioned changes can lead to a decrease in visual acuity and blindness. Treatment of ocular symptoms is mainly based on systemic therapy of the disease and local care. For a favourable outcome of the disease, timely establishment of the correct diagnosis and an interdisciplinary approach in management and treatment of patients with bullous dermatoses are required

Key words:
epidermolysis bullosa; epidermolysis bullosa acquisita; linear immunoglobulin A disease; mucous membrane pemphigoid; pemphigus vulgaris